Investigating How Gut Microbiota Influence Drug Metabolism and Disease Susceptibility

Introduction

The gut microbiota, a complex community of microorganisms residing in the gastrointestinal tract, plays a crucial role in human health. Recent research has highlighted its significant influence on drug metabolism and disease susceptibility. Understanding this relationship is essential for developing personalized medicine approaches and improving therapeutic outcomes.

The Role of Gut Microbiota in Drug Metabolism

Gut microbiota can affect the pharmacokinetics and pharmacodynamics of various drugs. The mechanisms through which microbiota influence drug metabolism include:

• Enzymatic Modification: Microbial enzymes can modify drugs, leading to changes in their efficacy and toxicity.